Arimidex (Anastrozole) It was originally developed in the early 90s to treat breast cancer in postmenopausal woman. How Arimidex (Anastrozole) works anytime an aromatizing steroid is used it will convert into Oestrogen then this leads to Oestrogen related problems such as, gynecomastia, bloating, water retention, heart strain, to name but a few. Arimidex (Anastrozole)works by blocking aromatize it doesn’t actually kill it but more of a suppressant that stops more Oestrogen from being produced when used on a cycle it will keep your Oestrogen under control since its so mild its not going to completely shut down your Oestrogen and make it to low which you don’t want to do. As a male, you still need Oestrogen in your body so Arimidexkeeps it in a balanced range. It also greatly increases testosterone in the body and can do so by as much as 50% by increasing total testosterone as well as Luteinizing Hormone (LH) and Follicle Stimulating Hormone (FSH) total output.